Although the Mugs/Cups/Tumblers cases of endometrial carcinoma (EC) is gradually increasing across the world, its etiology and pathogenesis remain unknown.The present study is the first to define the role and biological function of circRNA hsa_circ_0075960 in the development and progression of EC.We first determined that hsa_circ_0075960 is aberran

Cancer is a complex ailment orchestrated by numerous intrinsic and extrinsic pathways.Recent research has displayed a deep interest in developing plant-based cancer therapeutics for better management of the disease and limited side effects.A wide range of plant-derived compounds have been reported for their anticancer potential in the quest of find

Preterm premature rupture of membranes (PPROM) is in obstetrics with incidence of 0,4% of , with risk for chorioamnionitis 35%, risk for premature deli very 19%, and sepsis risk of 1%.Primary risk for fetus is pulmonal hypoplasia due to oligohydramnios in 29%, RDS in 66 % of such pregnancies, sepsis in 19%, and contracture of extremities in 3%.Feta

Background: Nasopharyngeal carcinoma (NPC) is a form of head and neck cancer that is endemic in most parts of Asia.Etiological factors for NPC include genetic disposition, consumption of a nitrosamine-rich diet, and Epstein-Barr virus (EBV) infection.One of the important EBV oncoproteins responsible for NPC pathogenesis is the Latent Membrane Prote

Most proteins of the TRIM family (also known as RBCC family) are ubiquitin ligases that share a peculiar protein structure, characterized by including an N-terminal RING finger domain closely followed by one or two B-boxes.Additional protein domains found at their C termini have been used to classify TRIM proteins into classes.TRIMs are involved in